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Recent advances and current developments in tissue scaffolding

Yarlagadda, Prasad K., Chandrasekharan, Margam, & Shyan, John Yong Ming (2005) Recent advances and current developments in tissue scaffolding. Bio-Medical Materials and Engineering, 15(3), pp. 159-177.

Abstract

A bio-scaffold can be broadly termed as a structure used to substitute an organ either permanently or temporarily to restore functionality. The material that can be used varies with the application intended. Tissue engineering is one such application demanding certain requirements to be met before it is applied. One of the applications in tissue engineering is the tissue scaffold, which provides either a permanent or temporary support to the damaged tissues/organ until the functionalities are restored. A biomaterial can exhibit specific interactions with cells that will lead to stereotyped responses. The use of a particular material and morphology depends on various factors such as osteoinduction, osteoconduction, angiogenesis, growth rates of cells and degradation rate of the material in case of temporary scaffolds, etc. The current work reviews the state of art in tissue scaffolds and focuses on permanent scaffold materials and applications with a brief overview of temporary scaffold materials and their disadvantages.

Impact and interest:

67 citations in Scopus
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48 citations in Web of Science®

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6,632 since deposited on 18 Oct 2007
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ID Code: 10231
Item Type: Journal Article
Additional URLs:
Keywords: Tissue scaffolding, titanium, bioactive materials, bone reconstruction
ISSN: 0959-2989
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Copyright Owner: Copyright 2005 IOS Press
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 18 Oct 2007
Last Modified: 29 Feb 2012 23:11

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