Myanmar dengue outbreak associated with displacement of serotypes 2, 3, and 4 by dengue 1

Thu, Hlaing Myat, Lowry, Kym S., Myint, Thein T., Shwe, Than N., Han, Aye M., Khin, Kyu K., Thant, Kyaw Z., Thein, Soe, & Aaskov, John G. (2004) Myanmar dengue outbreak associated with displacement of serotypes 2, 3, and 4 by dengue 1. Emerging Infectious Diseases, 10(4), pp. 593-597.

Abstract

In 2001, Myanmar (Burma) had its largest outbreak of dengue—15,361 reported cases of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), including 192 deaths. That year, 95% of dengue viruses isolated from patients were serotype 1 viruses belonging to two lineages that had diverged from an earlier, now extinct, lineage sometime before 1998. The ratio of DHF to DSS cases in 2001 was not significantly different from that in 2000, when 1,816 cases of DHF/DSS were reported and dengue 1 also was the most frequently isolated serotype. However, the 2001 ratio was significantly higher than that in 1998 (also an outbreak year) and in 1999, when all four serotypes were detected and serotypes 1, 2, and 3 were recovered in similar numbers. The large number of clinical cases in 2001 may have been due, in part, to a preponderance of infections with dengue 1 viruses.

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ID Code: 10508
Item Type: Journal Article
Refereed: Yes
Additional Information: The contents of this journal can be freely accessed online via the journal's web page (see hypertext link)
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ISSN: 1080-6040
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Copyright Owner: Copyright 2004 National Center for Infectious Diseases
Deposited On: 31 Oct 2007 00:00
Last Modified: 29 Feb 2012 13:27

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