Comparative clinical performance of two silicone hydrogel contact lenses for continuous wear

Morgan, Philip B. & Efron, Nathan (2002) Comparative clinical performance of two silicone hydrogel contact lenses for continuous wear. Clinical and Experimental Optometry, 85(3), pp. 183-192.

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BACKGROUND: Silicone hydrogel soft contact lenses are now available for use on a 30-day continuous wear basis. The aim of this study was to compare the clinical performance of two such lenses. METHODS: In a single-centre, randomised, subject-masked, two-period crossover study, 30 subjects wore a pair of PureVision lenses (Bausch & Lomb) and a pair of Focus Night & Day lenses (CIBA Vision), alternately, for successive eight-week periods. Assessment was made of lens fit and surface characteristics, logMAR visual acuity, ocular response and subjective reaction. RESULTS: Lens fit, deposition and post-lens debris were similar for the two lens types. High contrast visual acuity was statistically significantly better for the PureVision lens, as was the subject-reported quality of vision, although these differences were not considered clinically significant. For both lenses, limbal and conjunctival redness reduced throughout the duration of the study, whereas there was a slight increase in the overall amount of corneal staining. The incidence of mucin balls peaked four weeks after commencing lens wear and began to decline thereafter; more mucin balls were noticed in subjects wearing Focus Night & Day lenses. No differences between the lenses were observed for any other biomicroscopic signs. CONCLUSIONS: This study demonstrates similar clinical performance with the two silicone hydrogel lenses evaluated. We believe that, with careful monitoring, both of these new-generation lenses can be prescribed for continuous wear.

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ID Code: 10767
Item Type: Journal Article
Refereed: Yes
Additional Information: The contents of this journal from 1998 to 2005 can be freely accessed online via the journal’s web page (see link).
Additional URLs:
Keywords: comfort, continuous wear, mucin balls, silicone hydrogel contact lenses, vision
ISSN: 0816-4622
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2002 Optometrists Association Australia
Deposited On: 16 Nov 2007 00:00
Last Modified: 10 Aug 2011 16:16

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