The effect of fenestrating soft contact lenses on corneal oxygen availability

Efron, Nathan & Carney, Leo G. (1983) The effect of fenestrating soft contact lenses on corneal oxygen availability. American Journal Of Optometry And Physiological Optics, 60(6), pp. 503-508.


Recent clinical and experimental evidence suggests that a better physiological response to hydrogel lens wear can be obtained with fenestrations. To determine whether those observations could be attributed to increased corneal oxygenation, the equivalent oxygen percentage (EOP) was measured at the cornea of eight subjects wearing hydrogel contact lenses which had multiple fenestrations of 0.8 and 1.8 mm. It was possible to increase the mean EOP by 1.7 +/- 1.3% O2 (p less than 0.002) beneath a standard thickness lens using four 1.8-mm fenestrations. However, such lenses were uncomfortable to wear. Fenestrations that provided comfortable wear (0.8-mm diameter) did not significantly increase the EOP beneath standard thickness lenses (-0.1 +/- 1.0% O2, p greater than 0.1 for four fenestrations, and +0.2 +/- 1.2% O2, p greater than 0.1 for eight fenestrations) or ultrathin lenses (-0.1 +/- 1.3% O2 p greater than 0.1 for four fenestrations). It is concluded that fenestrations do not provide a clinically efficient means of increasing the oxygen tension beneath hydrogel contact lenses.

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ID Code: 10806
Item Type: Journal Article
Refereed: Yes
Additional Information: Self-archiving of the author-version is not yet supported by this publisher.
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ISSN: 0093-7002
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1983 Lippincott Williams & Wilkins
Deposited On: 19 Nov 2007 00:00
Last Modified: 21 Apr 2010 16:46

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