Defects in disposable contact lenses can compromise ocular integrity
To ascertain the prevalence of defects in disposable contact lenses, an Optimec JFC contact lens analyser (×16 magnification) was used to examine 150 Acuvue, 150 NewVues, and 150 SeeQuence lenses, all -3.00D in power. The percentage of each lens type found to be defective was: Acuvue 75%, NewVues 5%, and SeeQuence 9%. A single-center, simultaneously-controlled, double-masked, randomized study was conducted to determine whether such defects compromise ocular integrity. Each of 29 subjects wore a defective Acuvue lens in one eye and a non-defective Acuvue (control) lens in the other eye on an extended-wear basis for one week. Lenses with defects visible to the naked eye were excluded. Although there was no significant difference in vision, subjective sensation, or bulbar conjunctival hyperemia between eyes wearing defective vs. control lenses, a significantly greater ocular response was observed in eyes wearing defective lenses in the form of corneal epithelial microcysts (p = 0.04), corneal staining (p = 0.02), and conjunctival staining (p = 0.04). Two cases of peripheral corneal infiltrates were observed; both cases were unilateral and occurred in eyes wearing defective lenses. Such compromise may predispose the eye to more serious complications such as infection and corneal ulceration.
Impact and interest:
Citation counts are sourced monthly from and citation databases.
These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.
Citations counts from theindexing service can be viewed at the linked Google Scholar™ search.
|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal’s website (see hypertext link) or contact the author.|
|Keywords:||Disposable contact lenses, lens defects, corneal epithelial microcysts, corneal staining, corneal infiltrates, conjunctival staining|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
|Divisions:||Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1992 Elsevier|
|Deposited On:||27 Nov 2007|
|Last Modified:||21 Apr 2010 16:54|
Repository Staff Only: item control page