Acanthamoeba keratitis associated with disposable hydrogel contact lenses disinfected daily with a chlorine-based care system

Sarwar, Naheed, Griffith, Guy A.P., Loudon, Karen, Tullo, Andrew B., & Efron, Nathan (1993) Acanthamoeba keratitis associated with disposable hydrogel contact lenses disinfected daily with a chlorine-based care system. Journal of the British Contact Lens Association, 16(1), pp. 15-18.

View at publisher


Three patients developed acanthamoeba keratitis which was associated with the use of Acuvue disposable soft contact lenses between March 1991 and January 1992. All three patients removed their lenses each night, placed them in Softab disinfecting solution and discarded them every 2 weeks. Acanthamoeba polyphaga was cultured from the contact lens cases of two patients and from a corneal scrape of the third patient. All three patients were treated with intensive neomycin and propamidine isethionate. The keratitis resolved in two patients, but the third responded slowly to this therapy and the treatment was supplemented with topical polyhexamethylene biguanide; this patient is improving gradually, but is still under review. As is the case with all soft contact lenses worn on a daily basis, disposable lenses require a rigorous lens maintenance regime which should include rubbing and rinsing, preferably with a surfactant cleaner, and the use of an effective disinfecting solution.

Impact and interest:

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 10969
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal’s website (see hypertext link) or contact the author.
Keywords: Acanthamoeba keratitis, disposable soft contact lenses, Acuvue, Softab
DOI: 10.1016/S0141-7037(05)80004-7
ISSN: 1367-0484
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1993 Elsevier
Deposited On: 27 Nov 2007 00:00
Last Modified: 10 Aug 2011 17:57

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page