Hydrogel contact lens dehydration and oxygen transmissibility
Efron, Nathan & Morgan, Philip B. (1999) Hydrogel contact lens dehydration and oxygen transmissibility. The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, 25(3), pp. 148-151.
PURPOSE: Oxygen transmissibility is a key determinant of the physiological response of the cornea to contact lens wear. Because transmissibility is related to hydrogel water content, we conducted a study to determine the change in water content during lens wear and to quantify the impact any such change would have on transmissibility. METHODS: In a double masked clinical investigation, two subjects each wore 17 different pairs of contact lenses. Water content was measured before lens wear at 35 degrees C and immediately after 4 hours of contact lens wear. Contact lens oxygen transmissibilities were calculated on each occasion. RESULTS: The absolute changes in water content for the 17 lenses varied from +0.5% to -5.3%. For some lenses, this change in water content altered the lens oxygen transmissibilities to a clinically significant degree. The changes in water content and oxygen transmissibilities were greatest with FDA Group IV lenses. CONCLUSIONS: Dehydration during contact lens wear can alter the oxygen transmissibility of hydrogel lenses, and in some situations, this factor may be clinically significant.
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|Item Type:||Journal Article|
|Additional Information:||Self-archiving of the author-version is not yet supported by this publisher. For more information, please refer to the journal’s website (see hypertext link) or contact the author.|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
|Divisions:||Current > Research Centres > Centre for Health Research|
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1999 Lippincott Williams & Wilkins|
|Deposited On:||28 Nov 2007|
|Last Modified:||11 Aug 2011 02:16|
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