Review: Full body washing with skin antiseptics before surgery does not prevent surgical site infection
Data sources: Medline (2005), Cochrane Wounds Group Specialised Register (2005) (includes searches of Medline, CINAHL, EMBASE/Excerpta Medica, Cochrane Central Register of Controlled Trials, wound care journals, and relevant conference proceedings), reference lists of retrieved articles, and manufacturers of antiseptic products. Study selection and assessment: randomised controlled trials (RCTs) that compared preoperative full body bathing or showering using antiseptic solution with use of non-antiseptic soap or no full body wash in adults or children undergoing any type of surgery. 6 RCTs (n = 10 007) met the selection criteria. The antiseptic used in all trials was 4% chlorhexidine gluconate. Quality of RCTs was independently assessed by 2 reviewers based on randomisation method, allocation concealment, blinding, intention to treat analysis, and completeness of outcome reporting. Outcomes: surgical site infection (as defined in the original study), allergic reactions, costs. MAIN RESULTS Full body washing with chlorhexidine did not reduce the risk of surgical site infection more than full body washing with placebo or bar soap, or no shower or bath (table). In 1 RCT, full body washing with chlorhexidine reduced the risk of surgical site infection more than localised washing of the surgical site with chlorhexidine (table). 1 study (n = 3489) reported no difference between chlorhexidine and placebo for allergic reactions or overall costs. CONCLUSION Full body washing with skin antiseptics (4% chlorhexidine) before surgery does not prevent surgical site infection.
Impact and interest:
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|Item Type:||Journal Article|
|Keywords:||anti, infective agents (local), baths, chlorhexidine, preoperative care, surgical wound infection|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
|Copyright Owner:||Copyright 2006 BMJ Publishing Group Ltd and the Royal College of Nursing|
|Copyright Statement:||Reproduced in accordance with the copyright policy of the publisher.|
|Deposited On:||11 Dec 2007 00:00|
|Last Modified:||09 Jun 2010 12:51|
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