Corneal hydration control in contact lens wearers with diabetes mellitus

O'Donnell, Clare & Efron, Nathan (2006) Corneal hydration control in contact lens wearers with diabetes mellitus. Optometry And Vision Science, 83(1), pp. 22-26.


Purpose. The purpose of this study was to assess the acute swelling and recovery response to contact lens-induced corneal hypoxia in diabetic patients who wear contact lenses. Methods. A thick, low water content, soft contact lens was fitted under a light patch to one eye of 23 diabetic patients and one eye of 23 nondiabetic control subjects in a single-masked, controlled clinical study. After 2.5 hours an ultrasonic pachymeter was used to measure the induced corneal edema and the rate at which the cornea recovered to baseline thickness. Results. The induced corneal edema was significantly less for the diabetic patients compared with the nondiabetic control subjects (p ! 0.004). The corneas of the diabetic patients were found to recover from the induced edema at a similar rate to the corneas of the nondiabetic control subjects (p ! 0.28). Conclusions. Diabetes mellitus alters aspects of corneal hydration control. (Optom Vis Sci 2006;83:22–26)

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13 citations in Scopus
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11 citations in Web of Science®

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ID Code: 11263
Item Type: Journal Article
Refereed: Yes
Additional Information: The contents of this journal can be freely accessed online via the journal's web page (see hypertext link) 12 months after publication. Self-archiving of the author-version is not yet supported by this publisher.
For more information, please refer to the journal's website (see hypertext link) or contact the author.
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Keywords: diabetes, cornea, edema, percent recovery per hour, contact lens, complications
ISSN: 1040-5488
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2006 Lippincott Williams & Wilkins
Deposited On: 07 Jan 2008 00:00
Last Modified: 29 Feb 2012 13:30

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