Dynamic wettability of pHEMA-based hydrogel contact lenses

Maldonado-Codina, Carole & Efron, Nathan (2006) Dynamic wettability of pHEMA-based hydrogel contact lenses. Ophthalmic and Physiological Optics, 26(4), pp. 408-418.

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Standard methods of contact angle analysis include sessile drop, captive bubble and Wilhelmy plate techniques; however, these methodologies are not particularly well suited for assessing the wettability of the surfaces of formed hydrogel contact lenses. This paper describes two methodologies that are adaptations of previously described techniques. The maximum adherent force method is an adaptation of the dynamic Wilhelmy plate technique that allows the assessment of whole, finished contact lenses. The dynamic photographic method allows the simultaneous assessment of the front and back surfaces of strip samples for the assessment of advancing and receding contact angles. Lenses investigated were made from polyhydroxyethyl methacrylate, hydroxyethyl methacrylate/methacrylic acid and hydroxyethyl methacrylate/glycerol methacrylate. The lenses were manufactured by lathing, spin-casting or cast-moulding techniques. Overall, both techniques demonstrated few differences between the wettability of different lens materials and no differences between materials of the 'same' lens type but manufactured by different methods. These findings are consistent with the results of clinical studies, which have shown little difference between contact lens surface wettability in vivo, which may be due to the apparent natural surface wettability-enhancing properties of the pre-lens tear film.

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11 citations in Web of Science®

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ID Code: 11267
Item Type: Journal Article
Refereed: Yes
Additional Information: Pdf copy of the published version stored at I:\Support_for_Research\ePrints\FULLTEXT-DOCUMENTS\ERA-Trial
Keywords: contact angle, contact lens, manufacture, wettability
DOI: 10.1111/j.1475-1313.2006.00394.x
ISSN: 0275-5408
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Optometry & Vision Science
Copyright Owner: Copyright 2006 Blackwell Publishing
Copyright Statement: The definite version is available on publication at www3.interscience.wiley.com
Deposited On: 04 Jan 2008 00:00
Last Modified: 10 Aug 2011 15:52

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