Chronic morbidity of corneal infiltrative events associated with contact lens wear

Efron, Nathan, Morgan, Philip B., & Makrynioti, Dimitra (2007) Chronic morbidity of corneal infiltrative events associated with contact lens wear. Cornea, 26(7), pp. 793-799.

Abstract

PURPOSE: To determine the chronic morbidity of corneal infiltrative events (CIEs) associated with contact lens wear. METHODS: The central corneas of both eyes of 13 subjects who had suffered a CIE 27 +/- 4 months previously were examined by using slit-lamp biomicroscopy, confocal microscopy, and ultrasound pachometry. Snellen visual acuity was recorded in both eyes. A questionnaire was administered to ascertain the type and extent of changes in contact lens wear and care since suffering from the CIE. RESULTS: Slit-lamp biomicroscopy revealed the presence of a circular scar, approximately 1.5 mm in diameter, in the central cornea of the right eye of the patient who had suffered the most clinically severe CIE; no residual scar, or any other abnormality, was detected in any of the other 12 patients. No significant difference between the 2 eyes was found with respect to basal epithelial cell density; anterior or posterior keratocyte density; endothelial cell density, polymegethism, or pleomorphism; corneal thickness; or visual acuity. Anecdotally, however, markedly reduced pan-corneal cell counts, increased endothelial polymegethism, and reduced corneal thickness were observed in the affected eye of the patient who had suffered the most clinically severe CIE. After having suffered from a CIE, many patients changed lens type or brand, ceased to routinely sleep in lenses, or wore lenses less often. CONCLUSIONS: In general, contact lens-associated CIEs do not compromise the long-term integrity of the cornea. Changes in lens-related behaviors of patients who have suffered from a CIE seem to be aimed at reducing the risk of a further occurrence. Anecdotally, more severe CIEs may be associated with chronic tissue morbidity.

Impact and interest:

5 citations in Scopus
Search Google Scholar™
4 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 11277
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal's website (see hypertext link) or contact the author.
Additional URLs:
Keywords: contact lens, cornea, keratitis, corneal infiltrative event, morbidity, confocal microscope
ISSN: 0277-3740
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2007 Lippincott Williams & Wilkins
Deposited On: 20 Dec 2007 00:00
Last Modified: 29 Feb 2012 13:36

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page