Clinical analysis of screening and threshold visual field data for glaucoma detection
Wood, Joanne M., Swann, Peter G., & Eyeson-Annan, Margo (1992) Clinical analysis of screening and threshold visual field data for glaucoma detection. Clinical and Experimental Optometry, 75(3), pp. 81-88.
The value of clinical interpretation in differentiating between glaucomatous and normal fields from threshold (Humphrey Field Analyser) and screening (Henson CFS3000) measures was determined using a masked prospective experimental design. The visual field plots of 20 primary open-angled glaucoma (POAG) patients, 19 ocular hypertensive and 19 normotensive glaucoma suspects, and 21 age-matched normals measured with the Humphrey Field Analyser (Humphrey) and Henson CFS3000 (Henson) were catagorised by two experienced clinicians. Significant differences in interpretation of the field plots were demonstrated between the tow clinicians (chi-squares = 19.36; p<0.001). The sensitivity of clinical interpretation was shown to lie between 65 per cent and 90 per cent (dependant upon the individual clinician) for the Humphrey plots, but was as low as 40 per cent with the Henson plots. Specificity was, however, higher for the Henson overall, regardless of the clinician (between 90 per cent and 95 per cent) compared to the Humphrey (between 75 per cent and 100 per cent). These levels of sensitivity and specificity do not reach the levels reported when interpretation is based on the visual field indices alone. It was concluded that a screening instrument, such as the Henson, should only be employed for testing large unselected populations, in which the prevalence of glaucoma is low. Visual fields should not judged in isolation, but in conjunction with measures of optic nerve and nerve fiber layers integrity, intra-ocular pressure and family history.
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|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal's website (see hypertext link) or contact the author.|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
|Divisions:||Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1992 Optometrists Association Australia|
|Deposited On:||16 Jan 2008 00:00|
|Last Modified:||21 Apr 2010 15:59|
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