QUT ePrints

The effect of the lipid layer on tear film deposition and thinning

McElwain, D. L. S., Jones, M. B., Fulford, G., Collins, M. J., & Roberts, A. P. (2006) The effect of the lipid layer on tear film deposition and thinning. Clinical and Experimental Optometry, 89(2), pp. 113-114.

View at publisher

Abstract

This work mathematically models the effects of surfactants during tear film deposition and subsequent thinning. The surfactants occur naturally on the surface of the tear film in the form of a lipid layer. A lubrication model is developed that describes lipid spreading and the evolution of the tear film height during and after an opening blink. Numerical methods are applied to the model, which includes the effects of lipid concentration, surface tension, viscosity, evaporation and gravity. It is found that the lipid layer continues to spread upwards on the cornea after the opening blink, in agreement with experimental work. It is also shown that lipids play an important role in drawing the tear film up the cornea during the opening blink. Further non-uniform distributions of lipids may lead to a rapid thinning of the tear film behind the advancing lipid front, resulting in the formation of surface capillary waves or shocks. Preliminary tear-scope and fluorescein experiments were undertaken to visualise the motion of the lipid layer and any associated shocks immediately after a blink. Using the experimental data, lipid particles were tracked to determine the surface velocity and these results were compared to the model predictions.

Impact and interest:

Citation countsare sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 12125
Item Type: Journal Article
Additional Information: For more information, please refer to the journal's website (see hypertext link) or contact the author.
ISSN: 0816-4622
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > Mathematical Sciences
Current > Schools > School of Optometry & Vision Science
Past > Schools > School of Physical & Chemical Sciences
Copyright Owner: Copyright 2006 Blackwell Publishing
Deposited On: 18 Jan 2008
Last Modified: 22 Apr 2010 02:47

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page