The suitability of CR-39 and polysulphone for ocular solar ultraviolet (UV) dosimetry
Sydenham, Michael M., Collins, Michael J., & Hirst, Lawrence W. (1994) The suitability of CR-39 and polysulphone for ocular solar ultraviolet (UV) dosimetry. Investigative Ophthalmology and Visual Science, 35(4), p. 1327.
Purpose: To investigate the suitability of UV-sensitive polymers poly (allyl diglycol carbonate) (CR-39) and polysulphone (PS), for use as a contact lens dosimeter for ocular surface UV dose assessment. Methods: CR-39 and PS thin-sheet (n=500) and contact lens (n=30) dosimeters were exposed to unshaded sunlight from 0 to 9 MED in 1 MED steps (1 MED = 1 Minimal Erythemal Dose ≈ 18mJ.cm-2 @ 297nm). Following exposure, CR-39 dosimeters were etched in KOH to reveal UV-induced surface opacities, later quantified by spectrophotometry at 400nm and 720 nm. PS dosimeters were analysed for UV-induced change in absorbance at 330nm. Pilot studies were conducted to evaluate the wearability of a PS and CR-39 contact lenses on a human eye. Results: Both CR-39 and PS exhibited statistically significant dose-response trends (CR-39: ANOVA F9, 90 ≥ 13.362, p=0.0001; PS: ANOVA F9, 90 = 3650.6, p ≤ 0.0001). However, CR-39 was unable to discern 1 MED variation for less than 7 MED (0 vs. 7 MED: Sheffé F9, 90 ≥ 2.545, p < 0.05), while PS was accurate to 1 MED steps (e.g. 0 to 1 MED, 1 to 2 MED, etc.: Sheffé F9,90 ≥ 6.682, p < 0.05). Conclusion: Compared to CR-39, PS exhibited a superior dose-response trend for low solar UV dose. A ballasted PS contact lens offers a potentially powerful tool for the assessment of regional ocular UV dose using UV-fluorescence imaging techniques, currently under development.
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|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal’s website (see hypertext link) or contact the author.|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
|Divisions:||Current > Research Centres > Centre for Health Research|
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1994 Association for Research in Vision and Ophthalmology|
|Deposited On:||25 Jan 2008|
|Last Modified:||11 Aug 2011 00:40|
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