Multifocal ERG in multiple evanescent white dot syndrome
Feigl, Beatrix and Haas, Anton and El-Shabrawi, Yosuf (2002) Multifocal ERG in multiple evanescent white dot syndrome. Graefe's Archive for Clinical and Experimental Ophthalmology, 240(8). pp. 615-621.
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DOI : 10.1007/s00417-002-0478-7
Abstract
PURPOSE: To investigate the electrophysiological findings of a multifocal ERG in multiple evanescent white dot syndrome (MEWDS). METHODS: Multifocal electroretinograms (mf-ERG) were recorded from four patients with MEWDS. The stimulus array consisted of 61 hexagons and was presented according to a binary m-sequence. We analyzed the N1- and P1-wave amplitudes as well as P1 latencies of the first-order kernels. Local responses and concentric ring averaged responses were compared to 20 age-matched normal subjects. All patients underwent fluorescein angiography and indocyanine green angiography. RESULTS: In two patients, first-order kernel of N1- and P1-wave amplitudes showed supernormal results at the very beginning (day 1 to day 7) of the disease. By 2 weeks later, N1- and P1-wave amplitudes had decreased to either normal or subnormal values. The two patients who presented 2 weeks after the onset of clinical signs showed subnormal or decreased amplitudes. The P1 implicit times were within normal limits in all patients. CONCLUSION: Our mf-ERG findings show different results during the course of the disease. First-order kernel amplitudes seem to reflect early disturbances of the photoreceptors in MEWDS and are therefore useful in detecting early stages and following up the disease.
| ID Code: | 12448 |
|---|---|
| Item Type: | Journal Article |
| Additional Information : | For more information, please refer to the journal’s website (see hypertext link) or contact the author. |
| ISSN: | 1435-702X |
| Subjects: | Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303) Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302) |
| Divisions: | QUT Faculties and Divisions > Faculty of Health Research Centres > Centre for Health Research Institutes > Institute of Health and Biomedical Innovation |
| Copyright Owner : | Copyright 2002 Springer |
| Copyright Statement : | The original publication is available at SpringerLink http://www.springerlink.com |
| Deposited On: | 13 Feb 2008 |
| Last Modified: | 15 Jan 2009 18:06 |
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