Bilateral tremor relations in Parkinson's disease : Effects of mechanical coupling and medication

Morrison, Steven, Kerr, Graham K., & Silburn, Peter A. (2008) Bilateral tremor relations in Parkinson's disease : Effects of mechanical coupling and medication. Parkinsonism & Related Disorders, 14(4), pp. 298-308.

View at publisher


The aim of the present study was to examine the dynamics of bilateral multiple segment resting and postural tremor in 12 young, older subjects and eight Parkinson’s (PD) patients in their different medication states. A second aim was to investigate whether bilateral independence of upper limb tremor was preserved for PD patients with amplified tremor under conditions where no upper limb segment was supported. Under these conditions, the likelihood for mechanical transmission between segments was increased. Tremor was recorded, bilaterally, from the hand and finger segments of all subjects. In addition to the PD subjects exhibiting greater tremor under both on/off medication states than the young/old control subjects, the tremor increase within limb from the hand to the finger was 2–3 times greater for the PD group in comparison to the healthy subjects. Despite this increased tremor, no differences were observed in the level of coupling between limbs across groups. Furthermore, the degree of coupling between limbs for the PD group was unaffected by their medication state. Overall, these results demonstrate that bilateral independence of tremor in PD participants is preserved despite conditions which maximised the chance of increased coupling.

Impact and interest:

18 citations in Scopus
Search Google Scholar™
14 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 12962
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal's website (see hypertext link) or contact the author.
Keywords: Parkinson's disease, resting tremor, postural tremor, bimanual coupling
DOI: 10.1016/j.parkreldis.2007.09.004
ISSN: 1353-8020
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
Copyright Owner: Copyright 2007 Elsevier Ltd.
Deposited On: 11 Mar 2008 00:00
Last Modified: 25 Oct 2013 06:29

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page