Robust semi-automated path extraction for visualising stenosis of the coronary arteries
Mueller, Daniel C. & Maeder, Anthony (2008) Robust semi-automated path extraction for visualising stenosis of the coronary arteries. Computerized Medical Imaging and Graphics, 32(6), pp. 463-475.
Computed tomography angiography (CTA) is useful for diagnosing and planning treatment of heart disease. However, contrast agent in surrounding structures (such as the aorta and left ventricle) makes 3-D visualisation of the coronary arteries difficult. This paper presents a composite method employing segmentation and volume rendering to overcome this issue. A key contribution is a novel Fast Marching minimal path cost function for vessel centreline extraction. The resultant centreline is used to compute a measure of vessel lumen, which indicates the degree of stenosis (narrowing of a vessel). Two volume visualisation techniques are presented which utilise the segmented arteries and lumen measure. The system is evaluated and demonstrated using synthetic and clinically obtained datasets.
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