The effect of trabecular micro-architecture on vertebra biomechanics: A finite element investigation

McDonald, Katrina A., Pearcy, Mark J., & Adam, Clayton J. (2007) The effect of trabecular micro-architecture on vertebra biomechanics: A finite element investigation. In The Adelaide Centre for Spinal Research - Spinal Research Symposium V, 28-30 August 2007, Adelaide, Australia.

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700,000 vertebral fractures occur each year in the United States alone, 85% of which are associated with osteoporosis. Although the changes in trabecular bone micro-architecture accompanying osteoporosis are well documented, the mechanisms by which these changes affect overall spine biomechanics are not well established. This study presents the development of a microstructural model of an entire lumbar vertebral body to investigate the effects of changes in trabecular bone micro-architecture on the strength and stiffness of the vertebral body. The FE results showed that age-related reductions in trabecular thickness and increases in trabecular spacing dramatically reduced the stiffness of the trabecular core, and vertebral body as a whole. Further, the proportion of total load carried by the trabecular core diminished from 52% in the age<50 model to a negligible amount for the age>75 model.

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ID Code: 13856
Item Type: Conference Paper
Refereed: Yes
Keywords: vertebral fractures, osteoporosis, trabecular bone, micro, architecture, spine biomechanics, stiffness
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2007 (please consult author)
Deposited On: 24 Jun 2008 00:00
Last Modified: 12 Dec 2011 00:10

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