The Effect of Healthcare-Acquired Infection on Length of Hospital Stay and Cost

Graves, Nicholas, Weinhold, Diana, Tong, Edward, Birrell, Frances A., Doidge, Shane R., Ramritu, Prabha, Halton, Kate A., Lairson, David, & Whitby, Michael (2007) The Effect of Healthcare-Acquired Infection on Length of Hospital Stay and Cost. Infection Control and Hospital Epidemiology, 28(3), pp. 280-292.

View at publisher


Objective: To estimate the independent effect of a single lower respiratory tract, urinary tract, or 'other' healthcare-acquired infection on length-of-stay and variable costs, and to demonstrate the bias from omitted variables present in previous estimates. Design: Prospective cohort study Setting: A tertiary referral hospital and regional district hospital in South-East Queensland, Australia Patients: Adults ≥ 18 years of age with a minimum inpatient stay of one night admitted to selected clinical specialities Results: Urinary tract infections were not associated with an increase in length of hospital stay or variable costs. Lower respiratory tract infection was associated with an increase of 2.58 days in hospital and $AU24 of variable costs, whilst ‘Other’ sites of infection were associated with an increased length-of-stay of 2.61 days but not variable costs. Many other factors were found to be associated with increased length of stay and variable costs alongside HAI. The exclusion of these variables caused a positive bias in the estimates of the costs of HAI. Conclusions: The existing literature may overstate the costs of HAI due to bias and the existing estimates of excess cost may not make intuitive sense to clinicians and policy makers. Accurate estimates of the cost of HAI should be made and used in appropriately designed decision-analytic economic (i.e. cost-effectiveness) models that will make valid and believable predictions of the economic value of increased infection-control.

Impact and interest:

76 citations in Scopus
Search Google Scholar™
61 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

1,610 since deposited on 09 Jul 2008
26 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 14014
Item Type: Journal Article
Refereed: Yes
Keywords: healthcare, acquired, infection, costs, length of stay, bias
DOI: 10.1086/512642
ISSN: 0899-823X
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PUBLIC HEALTH AND HEALTH SERVICES (111700) > Epidemiology (111706)
Australian and New Zealand Standard Research Classification > ECONOMICS (140000) > APPLIED ECONOMICS (140200) > Health Economics (140208)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Medical Genetics (excl. Cancer Genetics) (110311)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Public Health & Social Work
Copyright Owner: Copyright 2007 University of Chicago Press
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 09 Jul 2008 00:00
Last Modified: 29 Feb 2012 13:38

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page