Prediction of bovine cartilage proteoglycan content using energy dispersive X-ray analysis or optical absorbance and a multivariate techniques-fourier transform infrared microspectroscopy model
Bowden, Joshua C., Rintoul, Llewellyn, Bostrom, Thor E., Pope, James M., & Wentrup-Byrne, Edeline (2007) Prediction of bovine cartilage proteoglycan content using energy dispersive X-ray analysis or optical absorbance and a multivariate techniques-fourier transform infrared microspectroscopy model. In Kneipp, Katrin, Aroca, Ricardo, Kneipp, Harald, & Wentrup-Byrne, Edeline (Eds.) New approaches in biomedical spectroscopy. American Chemical Society, Washington, D.C., pp. 377-390.
Two analytical techniques: optical absorbance of Safranin-O stained cartilage sections and energy dispersive X-ray analysis have been used to construct partial least squares models from Fourier transform infra red spectral data. These models can be used to semi-quantitatively predict proteoglycan content in cartilage sections. Valuable information about the spatial distribution of the constituents in native, degraded or even engineered cartilage, can be obtained when these are used in conjunction with infra red imaging techniques.
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|Item Type:||Book Chapter|
|Additional Information:||This article is freely available from the American Chemical Society website 12 months after the publication date. See links to publisher website in this record.|
|Subjects:||Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > PHYSICAL CHEMISTRY (INCL. STRUCTURAL) (030600) > Structural Chemistry and Spectroscopy (030606)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > MEDICAL BIOCHEMISTRY AND METABOLOMICS (110100) > Medical Biochemistry - Proteins and Peptides (incl. Medical Proteomics) (110106)
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Science and Technology|
|Copyright Owner:||Copyright 2007 American Chemical Society|
|Deposited On:||20 Oct 2008|
|Last Modified:||29 Feb 2012 23:40|
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