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A Pilot Study For Tissue Characterisation Using Bioimpedance Mapping

Smith, Jye G., Thomas, Brian J., & Cornish, Bruce H. (2007) A Pilot Study For Tissue Characterisation Using Bioimpedance Mapping. In Scharfetter, Hermann & Merwa, Robert (Eds.) 13th International Conference on Electrical Bioimpedance and the 8th Conference on Electrical Impedance Tomography ICEBI 2007, August 29th - September 2nd 2007, Graz, Austria.

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Abstract

Bioimpedance has shown potential as a method for characterising biological tissue with the use of the tetrapolar electrode configuration. This configuration has been shown to distinguish between normal squamous epithelium and Cervical Intra-epithelial Neoplasia (CIN) [1]. The tetrapolar configuration has also been shown to produce anomalous results in the form of an increase in measured impedance when a low impedance lesion is located between a drive and measurement electrode [2]. We have investigated a possible solution to this problem using bioimpedance mapping employing an array of 25 (5x5) electrodes. The array allows 64 individual tetrapolar measurements to be taken on 16 locations giving an impedance map of 49 mm2 on the surface of a tissue sample. Multiple measurements at each location reduce the chance of anomalous results since these can later be identified and excluded. Preliminary results on bovine blood have shown good separation of the measured impedance between areas of different haematocrit and provided a visual representation of the surface impedance. Impedance maps have been obtained for a range of haematocrit between 0 - 80%.

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ID Code: 15264
Item Type: Conference Paper
Keywords: Bioimpedance, Tetrapolar, Electrodes, Mapping
DOI: 10.1007/978-3-540-73841-1_40
ISBN: 9783540738411
ISSN: 1680-0737
Subjects: Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Synchrotrons; Accelerators; Instruments and Techniques (029904)
Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Biological Physics (029901)
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Copyright Owner: Copyright 2007 Springer
Copyright Statement: This is the author-version of the work. Conference proceedings published, by Springer Verlag, will be available via SpringerLink. http://www.springerlink.com SpringerLink
Deposited On: 20 Oct 2008
Last Modified: 29 Feb 2012 23:39

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