The clinical application of PET/CT: a contemporary review
Brady, Z., Taylor, M. L., Haynes, M., Whittaker, M., Mullen, A., Clews, L., Partridge, M. , Hicks, R. J., & Trapp, Jamie V. (2008) The clinical application of PET/CT: a contemporary review. Australasian Physical and Engineering Sciences in Medicine, 31(2), pp. 90-109.
The combination of positron emission tomography (PET) scanners and x-ray computed tomography (CT) scanners into a single PET/CT scanner has resulted in vast improvements in the diagnosis of disease, particularly in the field of oncology. A decade on from the publication of the details of the first PET/CT scanner, we review the technology and applications of the modality. We examine the design aspects of combining two different imaging types into a single scanner, and the artefacts produced such as attenuation correction, motion and CT truncation artefacts. The article also provides a discussion and literature review of the applications of PET/CT to date, covering detection of tumours, radiotherapy treatment planning, patient management, and applications external to the field of oncology.
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