# Numerical sequence representation of DNA sequences and methods to distinguish coding and non-coding sequences in a complete genome

Yu, Zu-Guo, Anh, Vo V., Zhou, Yu, & Zhou, Li-Qian
(2007)
Numerical sequence representation of DNA sequences and methods to distinguish coding and non-coding sequences in a complete genome. In
Callaos, N., Lesso, W., Zinn, C., & Zmazek, B. (Eds.)
*WMSCI 2007*, The International Institute of Informatics and Systemics (IIIS), Florida, USA, pp. 171-176.

## Abstract

In this presentation we introduce two methods to distinguish coding and non-coding sequences in a complete genome. A numerical sequence representation of DNA sequences is introduced first. There exists a one-to-one correspondence between a DNA sequence and its numerical sequence representation. In the first method, three exponents from a multifractal analysis are selected to construct the parameter space. In the second method, which is based on a Fourier transform approach, three parameters from the power spectrum of the numerical sequence representation are selected to construct the parameter space. Each DNA may be represented by a point in these three-dimensional spaces. We found that the points corresponding to coding and non-coding sequences in the complete genomes of prokaryotes are divided into different regions in both parameter spaces. If the point for a DNA sequence is situated in the region corresponding to coding sequences, the sequence is recognized as a coding sequence; otherwise, the sequence is classified as a non-coding one. The average accuracies using Fisher's discriminant algorithm for coding and non-coding sequences are satisfactory.

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ID Code: | 15651 |
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Item Type: | Conference Paper |

Refereed: | Yes |

Additional URLs: | |

ISBN: | 1934272140, 9781934272145 |

Subjects: | Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000) > APPLIED MATHEMATICS (010200) > Biological Mathematics (010202) Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > GENETICS (060400) > Genome Structure and Regulation (060407) |

Divisions: | Past > QUT Faculties & Divisions > Faculty of Science and Technology Current > Schools > School of Mathematical Sciences |

Copyright Owner: | Copyright 2007 (please consult author) |

Deposited On: | 18 Nov 2008 |

Last Modified: | 06 Mar 2015 00:48 |

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