Surface coatings for ventricular assist devices

Sin, Dong-Choon, Kei, Ho-Lun, & Miao, Xigeng (2009) Surface coatings for ventricular assist devices. Expert Review of Medical Devices, 6(1), pp. 51-60.

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This review focuses on the surface engineering of ventricular assist devices (VADs) for treating heart failing patients, which involves modification of the blood contacting surfaces to improve the blood compatibility (or heamocompatability) of the VADs. Following an introduction of the categorization and the complications of ventricular assist devices, this review pays attention to heamocompatability, applications, and limitations of six types of surface coatings for ventricular assist devices. The six types of surface coatings are: (1) titanium nitride (TiN) coatings, (2) diamond-like carbon (DLC) coatings, (3) 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coatings, (4) heparin coatings, (5) textured surfaces, and (6) endothelial cell lining. In particular, diamond-like coatings and heparin coatings are more commonly used than others for VADs due to their excellent haemocompatibility, durability, and technical maturity. For high performance and long lifetime of VADs, surface modification with coatings for haemocompatibility is as important as the mechanical design of VADs.

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35 citations in Scopus
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29 citations in Web of Science®

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ID Code: 15725
Item Type: Journal Article
Refereed: Yes
Keywords: ventricular assist device, surface coating, haemocompatibility, heparin, textured surface, endothelial cells
DOI: 10.1586/17434440.6.1.51
ISSN: 1743-4440
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2009 Expert Reviews Ltd.
Deposited On: 26 Nov 2008 00:00
Last Modified: 25 Oct 2013 00:38

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