Health-related quality of life 18 months after breast cancer : comparison with the general population of Queensland, Australia

DiSipio, Tracey, Hayes, Sandi, Newman, Beth M., & Janda, Monika (2008) Health-related quality of life 18 months after breast cancer : comparison with the general population of Queensland, Australia. Supportive Care in Cancer, 16(10), pp. 1141-1150.

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Goals of work Health-related quality of life (HRQoL) was compared between urban breast cancer survivors (BCS) and the general female population in urban Queensland, and correlates were identified. Materials and methods HRQoL data were collected at 6, 12, and 18 months post-diagnosis from a population-based sample of 287 women, aged 74 years or younger, diagnosed with breast cancer in 2002. The urban comparison group was drawn from a population-based survey conducted in 2004 and included 675 women aged 30–74 years with no prior history of breast cancer. The Functional Assessment of Cancer Therapy-General questionnaire was used to measure HRQoL in both groups. Main results Younger (<50 years) BCS reported lower HRQoL at 6 months (mean, 80.2 vs 86.8) but were comparable to the general population by 12 months post-diagnosis (mean = 87.3). In contrast, HRQoL of older (50+ years) BCS at 6 months (mean = 87.1) was comparable to their general population peers (mean = 86.0) and was clinically better 18 months post-diagnosis (mean = 91.0). Compared with the general population, physical and emotional well-being among younger BCS was impaired at 6 months post-diagnosis (mean, 24.9 vs 21.0 and 21.0 vs 18.0, respectively) and did not improve over time for emotional well-being (mean = 18.8). These results persisted after adjustment for treatment-related factors, although receiving chemotherapy was an important correlate of HRQoL among younger BCS at 6 months post-diagnosis (−14.9). Conclusions This study not only shows that the HRQoL of BCS improves between 6 and 18 months post-diagnosis but also suggests that emotional well-being among younger BCS may benefit from targeted intervention.

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25 citations in Scopus
21 citations in Web of Science®
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ID Code: 17656
Item Type: Journal Article
Refereed: Yes
Keywords: Breast cancer, General population comparisons, Longitudinal study, Oncology, Quality of life
DOI: 10.1007/s00520-007-0392-y
ISSN: 0941-4355
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Cancer Therapy (excl. Chemotherapy and Radiation Therapy) (111204)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 07 Apr 2009 00:20
Last Modified: 06 Jul 2017 06:01

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