QUT ePrints

Obesity, leanness, and mortality : effect modification by physical activity in men and women

Heitmann, Berit L., Hills, Andrew P., & Frederiksen, Peder (2008) Obesity, leanness, and mortality : effect modification by physical activity in men and women. Obesity, 17(1), pp. 136-142.

View at publisher

Abstract

The 13-year mortality from BMI, body fat (BF), and fat-free mass (FFM) was examined among active and sedentary adults. In total, 2,819 men and women aged 35–65 years in 1987/1988, participating in the Danish MONICA project, were included, and followed for 13.6 years for total mortality. In men, physical activity modified the health hazard of both a high and a low BMI, and the U-shaped association disappeared among the active (hazard ratio (HR) = 0.86, CI: 0.72–1.02). Among active men, FFM was inversely related to mortality (HR = 0.55, 95% CI: 0.40–0.77) whereas a direct positive trend was seen for BF. Among women, physical activity modified association between BMI and mortality, but the U-shaped association remained among the active. Among women, no significant associations were found between either BF or FFM and total mortality. All effects were independent of waist- and hip-circumferences. In conclusion, among men, physical activity may play an important role for the prevention of early mortality beyond its direct effects, by modifying the health hazard of both a high and a low BMI, and by lowering the risk associated with a high BF or a low FFM. Among women physical activity lowers mortality, but an effect-modifying potential of physical activity on associations between BMI or body composition could not be identified.

Impact and interest:

18 citations in Scopus
Search Google Scholar™
15 citations in Web of Science®

Citation countsare sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 18457
Item Type: Journal Article
Additional URLs:
Keywords: Obesity, Leanness, Physical activity, Mortality
DOI: 10.1038/oby.2008.479
ISSN: 19307381
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NUTRITION AND DIETETICS (111100) > Nutrition and Dietetics not elsewhere classified (111199)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
Deposited On: 14 Apr 2009 14:50
Last Modified: 29 Feb 2012 23:50

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page