Microbial keratitis and vision loss with contact lenses

Holden, Brien A., Sweeney, Deborah F., Sankaridurg, Padmaja, Carnt, Nicola, Edwards, Katie P., Stretton, Serina, & Stapleton, Fiona (2003) Microbial keratitis and vision loss with contact lenses. Eye & Contact Lens, 29(1 Suppl), pp. 131-134.

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Abstract

PURPOSE: Microbial keratitis is the only sight-threatening adverse event that occurs with contact lens wear. This article gives a preliminary estimation of the incidence of microbial keratitis and vision loss with continuous-wear contact lenses made from highly oxygen permeable (Dk) materials. METHODS: The most up-to-date data available on microbial keratitis and vision loss are collected from a range of sources including industry, private practice, and publications and is reviewed. RESULTS: There have been 16 cases of microbial keratitis with high-Dk silicone hydrogel lenses. Of the 13 where data are available, none have lost two or more lines of best-corrected visual acuity (BCVA). CONCLUSION: First approximation indicates that the incidence of microbial keratitis with high-Dk silicone hydrogel lenses may be lower than the incidence with low-Dk soft lenses during extended wear. The rate of loss of more than two lines of BCVA is low in patients that develop microbial keratitis with low- and high-Dk soft lenses.

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40 citations in Scopus
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ID Code: 20551
Item Type: Journal Article
Refereed: Yes
Additional Information: Accession Number: 12772749 Language: English. Date Revised: 20051116. Date Created: 20030529. Date Completed: 20030714. Update Code: 20081217. Publication Type: Case Reports; Journal Article; Review. Journal ID: 101160941. Publication Model: Print. Cited Medium: Print
Keywords: alcaligenes isolation & purification, contact lenses, extended-wear adverse effects, corneal ulcer microbiology, eye infections, bacterial etiology, gram-negative bacterial infections etiology, vision disorders etiology, adult, anti-infective agents therapeutic use, ciprofloxacin therapeutic use, corneal ulcer drug therapy, bacterial drug therapy, female, gram-negative bacterial infections drug therapy, humans, ophthalmic solutions, parasympatholytics therapeutic use, tropanes therapeutic use, vision disorders drug therapy
ISSN: 1542-2321
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 20 May 2009 23:04
Last Modified: 10 Aug 2011 17:43

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