Ocular and subjective responses to frequent replacement of daily wear soft contact lenses

Pritchard, Nicola, Fonn, Desmond, & Weed, Kathryn (1996) Ocular and subjective responses to frequent replacement of daily wear soft contact lenses. Eye and Contact Lens : Science and Clinical Practice, 22(1), pp. 53-59.

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PURPOSE: A significant number of soft contact lens wearers develop complications as a result of lens contamination. We conducted a single-blind 2 year clinical trial to determine if scheduled frequent replacement of lenses decreases complications.----- METHODS: One hundred nineteen non-contact lens wearers were fit with soft contact lenses and randomly assigned to 1 or 3 month replacement schedules or a non-replacement (control) group. All subjects were fit with 0.04 mm thick HEMA (water content: 38%) lenses to be worn on a daily wear basis only. A single multipurpose solution was prescribed for cleaning and disinfection.----- RESULTS: The 2-year results showed a significantly greater number of subjects in the non-replacement group exhibited microcysts, infiltrates, clinically significant corneal staining, and limbal and bulbar injection. As a result of lens deposition and damage, approximately twice the number of unscheduled lens replacements per subject were necessary in the non-replacement group compared with the 1 and 3 month replacement groups. Overall subject satisfaction with lens wear decreased in the non-replacement group and increased in the 1 and 3 month replacement groups over the 2-year period.----- CONCLUSIONS: Frequent replacement of soft lenses for daily wear as compared to non-replacement daily wear: 1) is less likely to cause contact lens induced complications; 2) reduces the number of unscheduled lens replacements; and 3) improves satisfaction with lens wear.

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ID Code: 20567
Item Type: Journal Article
Refereed: Yes
Additional Information: Accession Number: 8835070 Language: English. Date Revised: 20061115. Date Created: 19961217. Date Completed: 19961217. Update Code: 20081217. Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't. Journal ID: 8302065. Publication Model: Print. Cited Medium: Print
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Keywords: disposable equipment, patient satisfaction, contact lenses, eye diseases epidemiology & etiology, hydrophilic adverse effects, hydrogel, incidence, polyethylene glycols
ISSN: 0733-8902
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 25 May 2009 03:12
Last Modified: 10 Aug 2011 18:13

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