A Randomized Controlled Trial of an Educational Intervention for Managing Fatigue in Women Receiving Adjuvant Chemotherapy for Early Stage Breast Cancer
Yates, Patsy, Aranda, Sanchia, Hargraves, Maryanne, Mirolo, Bev, Clavarino, Alexandra, McLachlan, SueAnne, & Skerman, Helen M. (2005) A Randomized Controlled Trial of an Educational Intervention for Managing Fatigue in Women Receiving Adjuvant Chemotherapy for Early Stage Breast Cancer. Journal of Clinical Oncology, 23(25), pp. 6027-6036.
PURPOSE: To evaluate the efficacy of a psychoeducational intervention in improving cancer-related fatigue.
PATIENTS AND METHODS: A randomized controlled trial involving 109 women commencing adjuvant chemotherapy for stage 1 or 2 breast cancer in five day-chemotherapy treatment centers. Intervention group patients received an individualized fatigue education and support program delivered in the clinic and by phone over three 10-20 minute sessions one week apart. Instruments included: a numeric rating scale assessing confidence with managing fatigue; 11-point numeric rating scales measuring fatigue at worst, average, and best; FACT-F and Piper Fatigue Scales; Cancer Self-efficacy Scale; EORTC QLQ-C30; and the Hospital Anxiety and Depression Scale. For each outcome, separate analyses of covariance of change scores between baseline (T1) and the three follow-up time points (T2,T3,T4) were conducted, controlling for the variable’s corresponding baseline value.
RESULTS: Compared to the intervention group, mean difference scores between baseline (T1) and immediate post-test (T2) assessments increased significantly more for the control group for worst and average fatigue, FACT-F and Piper fatigue severity and interference measures. These differences were not observed between baseline and T3 and T4 assessments. No significant differences were identified for any pre-post test change scores for confidence with managing fatigue, cancer self-efficacy, anxiety, depression, or quality of life.
CONCLUSION: Preparatory education and support has the potential to assist women to cope with cancer-related fatigue in the short term. However, further research is needed to identify ways to improve the potency and sustainability of psychoeducational interventions for managing cancer-related fatigue.
Impact and interest:
Citation counts are sourced monthly from and citation databases.
These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.
Citations counts from theindexing service can be viewed at the linked Google Scholar™ search.
|Item Type:||Journal Article|
|Additional Information:||Self-archiving of the author-version is not yet supported by this publisher. For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: firstname.lastname@example.org|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000) > Clinical Nursing - Secondary (Acute Care) (111003)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000)
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2005 American Society of Clinical Oncology|
|Deposited On:||30 Nov 2006|
|Last Modified:||29 Feb 2012 13:10|
Repository Staff Only: item control page