A comprehensive nomenclature for serine proteases with homology to tissue kallikreins
Lundwall, Ake , Band, Vimla , Blaber, Michael , Clements, Judith, Courty, Yves , Diamandis, Eleftherios , Fritz, Hans , Lilja, Hans , Malm, Johan , Maltais, Lois , Olsson, A. Yvonne , Petraki, Constantina , Scorilas, Andreas , Sotiropoulou, Georgia , Stenman, Ulf-Hakan , Stephan, Carsten , Talieri, Maroulio , & Yousef, George (2006) A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biological Chemistry, 387(6), pp. 637-641.
The human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.
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|Item Type:||Journal Article|
|Keywords:||Evolution, Cancer, Hormone, Inflammation, Kininogen|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > GENETICS (060400) > Genome Structure and Regulation (060407)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Deposited On:||17 Jun 2009 23:14|
|Last Modified:||29 Jul 2013 13:47|
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