A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

Lundwall, Ake, Band, Vimla, Blaber, Michael, Clements, Judith, Courty, Yves, Diamandis, Eleftherios, Fritz, Hans, Lilja, Hans, Malm, Johan, Maltais, Lois, Olsson, A. Yvonne, Petraki, Constantina, Scorilas, Andreas, Sotiropoulou, Georgia, Stenman, Ulf-Hakan, Stephan, Carsten, Talieri, Maroulio, & Yousef, George (2006) A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biological Chemistry, 387(6), pp. 637-641.

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The human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

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ID Code: 22541
Item Type: Journal Article
Refereed: Yes
Keywords: Evolution, Cancer, Hormone, Inflammation, Kininogen
DOI: 10.1515/BC.2006.082
ISSN: 1431-6730
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > GENETICS (060400) > Genome Structure and Regulation (060407)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 17 Jun 2009 13:14
Last Modified: 29 Jul 2013 03:47

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