Reducing the global burden of depression : population level analysis of intervention cost-effectiveness in 14 world regions
Ayuso-Mateos, Jose Luis, Chisholm, Dan, Sanderson, Kristy, & Saxena, Shekhar (2004) Reducing the global burden of depression : population level analysis of intervention cost-effectiveness in 14 world regions. British Journal of Psychiatry, 184(5), pp. 393-403.
International evidence on the cost and effects of interventions for reducing the global burden of depression remain scarce.
Aims: To estimate the population-level cost-effectiveness of evidence-based depression interventions and their contribution towards reducing current burden.
Method: Primary-care-based depression interventions were modelled at the level of whole populations in 14 epidemiological subregions of the world. Total population-level costs (in international dollars or I$) and effectiveness (disability adjusted life years (DALYs) averted) were combined to form average and incremental cost-effectiveness ratios.
Results: Evaluated interventions have the potential to reduce the current burden of depression by 10–30%. Pharmacotherapy with older antidepressant drugs, with or without proactive collaborative care, are currently more cost-effective strategies than those using newer antidepressants, particularly in lower-income subregions.
Conclusions: Even in resource-poor regions, each DALYaverted by efficient depression treatments in primary care costs less than 1 year of average per capita income, making such interventions a cost-effective use of health resources. However, current levels of burden can only be reduced significantlyif there is a substantialincrease substantial increase intreatment coverage.
Impact and interest:
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|Item Type:||Journal Article|
|Divisions:||Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
|Deposited On:||17 Jun 2009 13:55|
|Last Modified:||12 Jul 2013 04:54|
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