Fresh-frozen vs irradiated allograft bone in orthopaedic reconstructive surgery

Costain, Darren J. & Crawford, Ross W. (2009) Fresh-frozen vs irradiated allograft bone in orthopaedic reconstructive surgery. Injury, 40(12), pp. 1260-1264.

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The use of allograft bone is increasingly common in orthopaedic reconstruction procedures. The optimal method of preparation of allograft bone is subject of great debate. Proponents of fresh-frozen graft cite improved biological and biomechanical characteristics relative to irradiated material, whereas fear of bacterial or viral transmission warrants some to favour irradiated graft. Careful review of the literature is necessary to appreciate the influence of processing techniques on bone quality. Whereas limited clinical trials are available to govern the selection of appropriate bone graft, this review presents the argument favouring the use of fresh-frozen bone allograft as compared to irradiated bone.

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30 citations in Scopus
29 citations in Web of Science®
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ID Code: 25856
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: allograft, irradiation, fresh-frozen, impaction graft, tissue processing, reconstruction
DOI: 10.1016/j.injury.2009.01.116
ISSN: 0020-1383
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2009 Elsevier Ltd.
Deposited On: 22 Jun 2009 02:10
Last Modified: 22 Jun 2017 08:19

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