Psychiatric disorder in HIV infection

Kelly, Brian, Raphael, Beverley, Judd, Fiona, Perdices, Michael, Kernutt, Graeme J., Burrows, Graham, Burnett, Paul C., & Dunne, Michael P. (1998) Psychiatric disorder in HIV infection. Australian and New Zealand Journal of Psychiatry, 32(3), pp. 441-453.

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Objective: This study aimed to investigate rates of psychiatric disorder in human immunodeficiency virus (HIV) infection, in an Australian sample of homosexual and bisexual men.

Method: A cross-sectional study of a total of 65 HIV sero-negative (HIV-) and 164 HIV sero-positive men (HIVt) (79 CDC stage 1 1/1 11 and 85 CDC stage IV) was conducted in three centres. Lifetime and current prevalence rates of psychiatric disorder were evaluated using the Diagnostic Interview Schedule Version lllR (DIS-IIIR). Results: Elevated current and lifetime rates of major depression were detected in both HIV negative and HIV positive homosexual/bisexual men. Lifetime rates of alcohol abuseldependence were significantly elevated in HIV positive men (CDC group IV) when compared with HIV negative men. Among the HIV positive group the majority of psychiatric disorders detected were preceded by a pre-HIV diagnosis of psychiatric disorder. Major depression represented the disorder most likely to have first onset after HIV infection diagnosis.

Conclusions: Lifetime rates of major depression were elevated in this sample of HIV-negative and HIV-positive men, In the HIV-positive men, psychiatric disorder was significantly associated with the presence of lifetime psychiatric disorder prior to HIV infection diagnosis, The findings indicate the importance of evaluation of psychiatric history prior to HIV infection and the clinical significance of depressive syndromes in this population.

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42 citations in Scopus
30 citations in Web of Science®
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ID Code: 27120
Item Type: Journal Article
Refereed: Yes
Keywords: Depression, Diagnostic Interview Schedule, HIV infection/AIDS, Psychiatric disorder
DOI: 10.3109/00048679809065539
ISSN: 0004-8674
Divisions: Current > QUT Faculties and Divisions > Division of Research and Commercialisation
Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Public Health & Social Work
Copyright Owner: Copyright 1998 Taylor and Francis
Deposited On: 31 Aug 2009 22:53
Last Modified: 10 Aug 2011 17:00

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