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Persistent chlamydial infections : role in inflammation and challenges for vaccine development.

Hafner, Louise M. & Timms, Peter (2005) Persistent chlamydial infections : role in inflammation and challenges for vaccine development. Mucosal Immunology Update, 13(4), pp. 4-7.

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Abstract

The development of chlamydial vaccines continues to be a major challenge for researchers. While acute infections are the main target of vaccine development groups, Chlamydia is well known for its ability to establish chronic or persistent infections in its host. To date, little effort has focussed specifically on the challenges of vaccines to successfully combat the chronic or persistent phase of the disease and yet this will be a necessary aspect of any fully successful chlamydial vaccine. This short review specifically examines the phenomenon of chlamydial persistence and the unique challenges that this brings to vaccine development.

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ID Code: 28805
Item Type: Journal Article
Keywords: Chlamydia, Persistence, Vaccine Development
ISSN: 1068-7629
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Life Sciences
Copyright Owner: Copyright 2005 Society for Mucosal Immunology/Nature Publishing Group
Deposited On: 24 Nov 2009 15:49
Last Modified: 10 Jun 2010 00:11

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