Persistent chlamydial infections : role in inflammation and challenges for vaccine development.
The development of chlamydial vaccines continues to be a major challenge for researchers. While acute infections are the main target of vaccine development groups, Chlamydia is well known for its ability to establish chronic or persistent infections in its host. To date, little effort has focussed specifically on the challenges of vaccines to successfully combat the chronic or persistent phase of the disease and yet this will be a necessary aspect of any fully successful chlamydial vaccine. This short review specifically examines the phenomenon of chlamydial persistence and the unique challenges that this brings to vaccine development.
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|Item Type:||Journal Article|
|Keywords:||Chlamydia, Persistence, Vaccine Development|
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Science and Technology|
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Life Sciences
|Copyright Owner:||Copyright 2005 Society for Mucosal Immunology/Nature Publishing Group|
|Deposited On:||24 Nov 2009 15:49|
|Last Modified:||10 Jun 2010 00:11|
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