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Clinical efficacy and safety of zoledronic acid in osteoporosis and Paget's disease

Doggrell, Sheila (2009) Clinical efficacy and safety of zoledronic acid in osteoporosis and Paget's disease. Expert Review of Endocrinology and Metabolism, 4(5), pp. 405-415.

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Abstract

Osteoporosis and Paget’s bone disease are the most common diseases of the bone. In addition to glucocorticoid treatment, there are many other secondary causes of osteoporosis. Bisphosphonates are used to treat these bone conditions. Zoledronic acid is the most potent bisphosphonate at inhibiting bone resorption. In osteoporosis, zoledronic acid increases bone mineral density for at least 1 year following a single intravenous administration. The efficacy and safety of zoledronic acid in the treatment of osteoporosis and Paget’s bone disease are reviewed. This article also covers the studies of the effects of zoledronic acid in the bone loss associated with the secondary osteoporosis.

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ID Code: 29668
Item Type: Journal Article
Keywords: zoledronic acid, osteoporosis, Paget's bone disease, clinical trials
DOI: 10.1586/eem.09.23
ISSN: 1744-6651
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PHARMACOLOGY AND PHARMACEUTICAL SCIENCES (111500) > Clinical Pharmacology and Therapeutics (111502)
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Past > Schools > School of Life Sciences
Copyright Owner: Copyright 2009 Expert Reviews Ltd.
Deposited On: 14 Jan 2010 08:56
Last Modified: 27 May 2011 00:55

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