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Cardiac state diagnosis using higher order spectra of heart rate variability

Chua, K.C., Chandran, V., Acharya, R. , & Lim, C.M. (2008) Cardiac state diagnosis using higher order spectra of heart rate variability. Journal of Medical Engineering & Technology, 32(2), pp. 145-155.

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Abstract

Heart rate variability (HRV) refers to the regulation of the sinoatrial node, the natural pacemaker of the heart, by the sympathetic and parasympathetic branches of the autonomic nervous system. Heart rate variability analysis is an important tool to observe the heart's ability to respond to normal regulatory impulses that affect its rhythm. A computer-based intelligent system for analysis of cardiac states is very useful in diagnostics and disease management. Like many bio-signals, HRV signals are nonlinear in nature. Higher order spectral analysis (HOS) is known to be a good tool for the analysis of nonlinear systems and provides good noise immunity. In this work, we studied the HOS of the HRV signals of normal heartbeat and seven classes of arrhythmia. We present some general characteristics for each of these classes of HRV signals in the bispectrum and bicoherence plots. We also extracted features from the HOS and performed an analysis of variance (ANOVA) test. The results are very promising for cardiac arrhythmia classification with a number of features yielding a p-value < 0.02 in the ANOVA test.

Impact and interest:

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ID Code: 30835
Item Type: Journal Article
Keywords: Higher Order Spectra, Heart Rate Variability, Cardiac State, Signal Analysis, Classification
DOI: 10.1080/03091900601050862
ISSN: 1464-522X
Subjects: Australian and New Zealand Standard Research Classification > INFORMATION AND COMPUTING SCIENCES (080000) > ARTIFICIAL INTELLIGENCE AND IMAGE PROCESSING (080100) > Pattern Recognition and Data Mining (080109)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > ELECTRICAL AND ELECTRONIC ENGINEERING (090600) > Signal Processing (090609)
Divisions: Current > Schools > School of Electrical Engineering & Computer Science
Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Past > Institutes > Information Security Institute
Past > Schools > School of Engineering Systems
Deposited On: 12 Feb 2010 22:48
Last Modified: 28 Mar 2014 13:51

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