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Can tissue engineering concepts advance tumor biology research?

Hutmacher, Dietmar W., Loessner, Daniela, Rizzi, Simone C., Kaplan, David, Mooney, David J., & Clements, Judith A. (2010) Can tissue engineering concepts advance tumor biology research? Trends in Biotechnology, 28(3), pp. 125-133.

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Abstract

Advances in tissue engineering have traditionally led to the design of scaffold- or matrix-based culture systems that better reflect the biological, physical and biochemical environment of the natural extracellular matrix. Although their clinical applications in regenerative medicine tend to receive most of the attention, it is obvious that other areas of biomedical research could be well served by the powerful tools that have already been developed in tissue engineering. In this article, we review the recent literature to demonstrate how tissue engineering platforms can enhance in vitro and in vivo models of tumorigenesis and thus hold great promise to contribute to future cancer research.

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56 citations in Scopus
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44 citations in Web of Science®

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ID Code: 31033
Item Type: Review
Keywords: tissue engineering, cancer research, in vivo models, in vitro models
DOI: 10.1016/j.tibtech.2009.12.001
ISSN: 0167-7799
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Past > QUT Faculties & Divisions > Faculty of Science and Technology
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Engineering Systems
Deposited On: 25 Feb 2010 14:27
Last Modified: 01 Mar 2012 00:24

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