Corneal Oxygenation: Blink Frequency as a Variable in Rigid Contact Lens Wear
Using a micropolarographic system, we measured the responses of six human corneas to nine oxygen exposure conditions: to air (continuous open-eye) with no contact lens in place, and to eight interblink intervals (1, 2, 3, 4, 5, 6, 7, and 300 s durations) with an oxygen impermeable lens in place. The corneal oxygen uptake rates immediately following each of those conditions were direct indices of tear bulk-flow exchange under a rigid contact lens as an oxygen route. Greatest efficiencies in reducing corneal oxygen demand were associated with the two highest blink frequencies examined (namely, for interblink intervals of 2 s or less). Even at those frequencies oxygen demands ranging from 4 to 6 times the open-eye, non-wearing, baseline rate for each eye typically occurred, clearly justifying the need for a supplementary oxygenation route, for example, directly through rigid contact lens materials having inherently high oxygen permeabilities.
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|Item Type:||Journal Article|
|Keywords:||Blinking, Contact Lenses, Cornea/, metabolism, Oxygen/, metabolism, Adult, Female, Humans, Male, Research Support, U, S, Gov't, P, H, S, Time Factors|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1990 BMJ Publishing Group|
|Copyright Statement:||Reproduced in accordance with the copyright policy of the publisher.|
|Deposited On:||15 Sep 2006|
|Last Modified:||09 Jun 2010 22:29|
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