Effect of topical anaesthesia on corneal epithelial fragility

Carney, Leo G., O'Leary, Daniel J., & Millodot, Michel (1984) Effect of topical anaesthesia on corneal epithelial fragility. International Ophthalmology, 7(2), pp. 71-73.

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The effect of topical anaesthetics on human corneal integrity was assessed by measurement of the alterations they cause in corneal damage threshold. The anaesthetics investigated were 1.0% Amethocaine HCl, assessed immediately after instillation and after delays of 20 min and 60 min, and 0.5% Amethocaine HCl and 0.4% Benoxinate HCl, assessed 20 min after instillation. At 20 min after instillation of 1.0% Amethocaine HCl, the corneal damage threshold was significantly decreased. At other times for this anaesthetic, and for 0.5% Amethocaine HCl and 0.4% Benoxinate HCl, the corneal damage threshold was unaltered.

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10 citations in Scopus
7 citations in Web of Science®
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ID Code: 3158
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: l.carney@qut.edu.au
Keywords: Anesthetics, Local/, toxicity, Cornea/, drug effects, Procaine/, analogs & derivatives, Tetracaine/, toxicity, Epithelium/drug effects, Humans, Procaine/toxicity, Time Factors
DOI: 10.1007/BF00165107
ISSN: 1573-2630
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 1984 Springer
Copyright Statement: The original publication is available at SpringerLink
Deposited On: 30 Jan 2006 00:00
Last Modified: 15 Jan 2009 06:54

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