Effect of fenestration soft contact lenses on corneal oxygen availability
Recent clinical and experimental evidence suggests that a better physiological response to hydrogel lens wear can be obtained with fenestrations. To determine whether those observations could be attributed to increased corneal oxygenation, the equivalent oxygen percentage (EOP) was measured at the cornea of eight subjects wearing hydrogel contact lenses which had multiple fenestrations of 0.8 and 1.8 mm. It was possible to increase the mean EOP by 1.7 +/- 1.3% O2 (p less than 0.002) beneath a standard thickness lens using four 1.8-mm fenestrations. However, such lenses were uncomfortable to wear. Fenestrations that provided comfortable wear (0.8-mm diameter) did not significantly increase the EOP beneath standard thickness lenses (-0.1 +/- 1.0% O2, p greater than 0.1 for four fenestrations, and +0.2 +/- 1.2% O2, p greater than 0.1 for eight fenestrations) or ultrathin lenses (-0.1 +/- 1.3% O2 p greater than 0.1 for four fenestrations). It is concluded that fenestrations do not provide a clinically efficient means of increasing the oxygen tension beneath hydrogel contact lenses.
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|Item Type:||Journal Article|
|Keywords:||Contact Lenses, Hydrophilic, Oxygen Consumption, Cornea/, metabolism, Refractive Errors/, therapy, Adult, Female, Humans, Male, Refractive Errors/metabolism, Visual Acuity|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1983 American Academy of Optometry|
|Copyright Statement:||Reproduced in accordance with the copyright policy of the publisher.|
|Deposited On:||25 Jan 2006|
|Last Modified:||09 Jun 2010 12:29|
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