The cost effectiveness of Naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence

Walters, David, Connors, Jason, Feeney, Gerald, & Young, Ross McD. (2009) The cost effectiveness of Naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence. Journal of Addictive Diseases, 28(2), pp. 137-144.

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he purpose of this study was to evaluate the comparative cost of treating alcohol dependence with either cognitive behavioral therapy (CBT) alone or CBT combined with naltrexone (CBT+naltrexone). Two hundred ninety-eight outpatients dependent on alcohol who were consecutively treated for alcohol dependence participated in this study. One hundred seven (36%) patients received adjunctive pharmacotherapy (CBT+naltrexone). The Drug Abuse Treatment Cost Analysis Program was used to estimate treatment costs. Adjunctive pharmacotherapy (CBT+naltrexone) introduced an additional treatment cost and was 54% more expensive than CBT alone. When treatment abstinence rates (36.1% CBT; 62.6% CBT+naltrexone) were applied to cost effectiveness ratios, CBT+naltrexone demonstrated an advantage over CBT alone. There were no differences between groups on a preference-based health measure (SF-6D). In this treatment center, to achieve 100 abstainers over a 12-week program, 280 patients require CBT compared with 160 CBT+naltrexone. The dominant choice was CBT+naltrexone based on modest economic advantages and significant efficiencies in the numbers needed to treat.

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ID Code: 32097
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: Cost-Effectiveness, CBT, Alcohol Treatment, Naltrexone
DOI: 10.1080/10550880902772456
ISSN: 1055-0887
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Psychiatry (incl. Psychotherapy) (110319)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Psychology & Counselling
Deposited On: 19 May 2010 22:27
Last Modified: 29 Feb 2012 14:09

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