New directions for the characterisation of cartilage health in vivo
Brown, Cameron P., Oloyede, Adekunle, Moody, Hayley R., & Crawford, Ross W. (2005) New directions for the characterisation of cartilage health in vivo. In Third IASTED International Conference on Biomechanics, September 7-9, 2005, Spain.
This paper outlines the motivation and preliminary investigations into the possibility of a new method of characterising cartilage health in vivo. Current in vivo indentation techniques, which rely on stiffness measurements alone, are unable to adequately distinguish between healthy and degraded tissue. By considering the tangential strain in the articular surface during an indentation test, it is hypothesised that a simple and more sensitive indicator of cartilage integrity may be possible. The present study investigates the effects of low levels of degradation on the tangential surface strain under the indenter. Preliminary results suggest that this technique is highly sensitive, and can discriminate between degeneration and the natural variations across the joint. From these investigations we propose that the relationship between indentation and the surrounding strain field might be able to distinguish between healthy soft tissue and degraded tissue in vivo, important information not available from the current techniques.
This study forms the basis of a series of further experimental and modelling investigations to develop these ideas with the goal of creating a more effective diagnostic method for the surgeon.
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|Item Type:||Conference Paper|
|Keywords:||articular cartilage, arthroscopic indentation, osteoarthritis, tangential surface strain|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomedical Engineering not elsewhere classified (090399)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering|
|Copyright Owner:||Copyright 2005 ACTA Press|
|Copyright Statement:||Reproduced in accordance with the copyright policy of the publisher.|
|Deposited On:||31 Jan 2006|
|Last Modified:||29 Feb 2012 23:13|
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