A modified cementing technique using BoneSource to augment fixation of the acetabulum in a sheep model
Timperley, A John, Nusem, Iulian, Wilson, Kathy, Whitehouse, Sarah L, Buma, Pieter, & Crawford, Ross W (2010) A modified cementing technique using BoneSource to augment fixation of the acetabulum in a sheep model. Acta Orthopaedica, 81(4), pp. 503-507.
Background and purpose
Our aim was to prove in an animal model that the use of HA paste at the cement-bone interface in the acetabulum would improve fixation. We examined, in sheep, the effect of interposing a layer of hydroxyapatite cement around the periphery of a polyethylene socket prior to fixing it using polymethylemethacrylate (PMMA).
We made a randomized study involving 22 sheep to test whether the application of BoneSource hydroxyapatite material to the surface of the ovine acetabulum prior to cementing a polyethylene cup at hip arthroplasty improved the fixation and the nature of the interface. We studied the gross radiographical appearance of the implant-bone interface and the histological appearance at the interface.
There were more radiolucencies evident in the control group. Histologically, only sheep randomized into the BoneSource group exhibited a fully osseointegrated interface.
Use of the hydroxyapatite material did not confer any detrimental effects. In some cases the material appeared to have been fully resorbed. When the material was evident on histological section, it was incorporated into an osseointegrated interface. There was no giant cell reaction present in any case. There was no evidence of migration of BoneSource to the articulation.
The application of HA material prior to cementation of a socket produced an improved interface. The technique may be useful in man with to extend the longevity of the cemented implant by protecting the socket interface from the effect of hydrodynamic fluid flow and particulate debris.
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|Item Type:||Journal Article|
|Additional Information:||Full text available free online - see DOI link above.|
|Keywords:||total hip replacement, hydroxyapatite, sheep model, polyethylene cup|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)|
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering|
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Engineering Systems
|Copyright Owner:||Copyright 2010 Taylor & Francis Ltd.|
|Deposited On:||22 Jul 2010 12:19|
|Last Modified:||01 Mar 2012 00:20|
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