Physiological response of the contralateral cornea to monocular hydrogel contact lens wear

Efron, Nathan, Kotow, Michael, Martin, Donald K., & Holden, Brien A. (1984) Physiological response of the contralateral cornea to monocular hydrogel contact lens wear. American Journal of Optometry and Physiological Optics, 61(8), pp. 517-522.


Previous authors have suggested that monocular contact lens wear can induce changes in the contralateral eye. However, most of these contralateral responses have yet to be substantiated or satisfactorily explained. This paper reports a randomized, controlled, single-masked experiment in which corneal thickness, corneal oxygen consumption, and the endothelial bleb response were monitored for 3 hr in both eyes of eight unadapted subjects who wore thick hydrogel lenses on one eye only. No significant contralateral effect was observed in any of the parameters examined. These findings reaffirm the validity of using the contralateral eye as a control in experiments with hydrogel contact lenses.

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9 citations in Scopus
9 citations in Web of Science®
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ID Code: 3339
Item Type: Journal Article
Refereed: Yes
Additional Information: Self-archiving of the author-version is not yet supported by this publisher.
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Keywords: Contact Lenses, Hydrophilic, Cornea/, physiology, Adult, Endothelium/physiology, Female, Humans, Male, Oxygen Consumption, Research Support, Non, U, S, Gov't
ISSN: 1040-5488
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 1984 Lippincott Williams & Wilkins
Deposited On: 03 Feb 2006 00:00
Last Modified: 10 Aug 2011 15:56

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