Intersubject variability in corneal swelling response to anoxia
Efron, Nathan (1986) Intersubject variability in corneal swelling response to anoxia. Acta Ophthalmologica Scandinavica, 64(3), pp. 302-305.
A controlled, double-masked, randomized experiment was conducted on 9 human subjects, to determine whether there is an intersubject difference in the corneal swelling response to anoxia. A statistically significant intersubject variability was observed (P less than 0.001), with oedema ranging from a mean of 3.6% to 7.3% following 3 h exposure to humidified nitrogen gas (anoxia). This result supports the hypothesis of previous workers that the intersubject difference in the corneal oedema response to a thick HEMA "stress lens" is due to oxygen deprivation and not some other physiological variable resulting from lens wear.
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|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: firstname.lastname@example.org|
|Keywords:||Anoxia/, physiopathology, Corneal Diseases/, etiology, Edema/, etiology, Adult, Anoxia/chemically induced, Clinical Trials, Contact Lenses/adverse effects, Double, Blind Method, Female, Humans, Male, Nitrogen, Random Allocation, Species Specificity|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1986 Blackwell Publishing|
|Deposited On:||08 Feb 2006|
|Last Modified:||15 Jan 2009 16:56|
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