Intersubject variability in corneal swelling response to anoxia
Efron, Nathan (1986) Intersubject variability in corneal swelling response to anoxia. Acta Ophthalmologica Scandinavica, 64(3), pp. 302-305.
Abstract
A controlled, double-masked, randomized experiment was conducted on 9 human subjects, to determine whether there is an intersubject difference in the corneal swelling response to anoxia. A statistically significant intersubject variability was observed (P less than 0.001), with oedema ranging from a mean of 3.6% to 7.3% following 3 h exposure to humidified nitrogen gas (anoxia). This result supports the hypothesis of previous workers that the intersubject difference in the corneal oedema response to a thick HEMA "stress lens" is due to oxygen deprivation and not some other physiological variable resulting from lens wear.
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| ID Code: | 3350 |
|---|---|
| Item Type: | Journal Article |
| Additional Information: | For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: n.efron@qut.edu.au |
| Additional URLs: | |
| Keywords: | Anoxia/, physiopathology, Corneal Diseases/, etiology, Edema/, etiology, Adult, Anoxia/chemically induced, Clinical Trials, Contact Lenses/adverse effects, Double, Blind Method, Female, Humans, Male, Nitrogen, Random Allocation, Species Specificity |
| ISSN: | 1395-3907 |
| Subjects: | Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Health Current > Institutes > Institute of Health and Biomedical Innovation |
| Copyright Owner: | Copyright 1986 Blackwell Publishing |
| Deposited On: | 08 Feb 2006 |
| Last Modified: | 15 Jan 2009 16:56 |
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