Vascular response of the cornea to contact lens wear
Efron, Nathan (1987) Vascular response of the cornea to contact lens wear. Journal of the American Optometric Association, 58(10), pp. 836-846.
The subject of contact lens-induced corneal vascularization has attracted considerable interest in recent times in view of the relatively high prevalence of this condition with the use of extended wear soft lenses. This paper reviews clinical features and underlying mechanisms of the vascular response to lens wear. The concept of a "normal" vascular response to contact lens wear is proposed; the limits of this response are defined and incorporated into a simple grading system. The clinical presentation of vessel growth in the cornea is described together with appropriate methods of slit lamp evaluation. Current theories of the pathology and etiology of lens-induced vascularization are reviewed, and a dual-etiology model of stromal vessel formation is described. It is concluded that the prognosis for halting the progression of vascularization is excellent; however, little information is available concerning the long-term regression of "ghost" vessels.
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|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal's website (see link) or contact the author. Author contact details: firstname.lastname@example.org|
|Keywords:||Contact Lenses, Extended, Wear/, adverse effects, Contact Lenses, Hydrophilic/, adverse effects, Cornea/, blood supply, Corneal Diseases/, pathology, Neovascularization, Pathologic/, pathology, Cornea/pathology, Corneal Diseases/epidemiology, Corneal Diseases/etiology, Corneal Diseases/therapy, Humans, Neovascularization, Pathologic/epidemiology, Neovascularization, Pathologic/etiology, Neovascularization, Pathologic/therapy, Prognosis|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 1987 Elsevier|
|Deposited On:||08 Feb 2006 00:00|
|Last Modified:||15 Jan 2009 06:56|
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