The effect of soft lens lubricants on symptoms and lens dehydration

Efron, Nathan, Golding, Timothy R., & Brennan, Noel A. (1991) The effect of soft lens lubricants on symptoms and lens dehydration. The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, 17(2), pp. 114-119.


In order to establish the efficacy of soft lens lubricants and their mode of action, we conducted a controlled, double-masked, randomized study. Symptoms of dryness as well as lens water content were assessed in 30 symptomatic hydroxyethylmethacrylate (HEMA) contact lens wearers who each applied either saline or one of two soft lens lubricants every 2 hours over a 6-hour wearing period. Short- and long-term symptomatic relief from ocular dryness was provided by both lens lubricants (ANOVA, P less than .05). However, neither lubricant was found to be significantly superior to saline. Contact lens dehydration was not significantly reduced by the instillation of any solution. A psychological rather than a physical (lens hydration) or physiological basis to the symptomatic relief provided by soft lens lubricants cannot be discounted.

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ID Code: 3373
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal’s website (see link) or contact the author. Author contact details:
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Keywords: Contact Lenses, Hydrophilic/, adverse effects, Dry Eye Syndromes/, therapy, Ophthalmic Solutions/, therapeutic use, Adolescent, Adult, Analysis of Variance, Desiccation, Double, Blind Method, Dry Eye Syndromes/etiology, Female, Humans, Lubrication, Male, Methacrylates, Research Support, Non, U, S, Gov't
ISSN: 0733-8902
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1991 Contact Lens Association of Ophthalmologists
Deposited On: 17 Feb 2006 00:00
Last Modified: 10 Aug 2011 13:21

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