Standardization and omics science : technical and social dimensions are inseparable and demand symmetrical study

Holmes, Christina, McDonald, Fiona, Jones, Mavis, Ozdemir, Vuril, & Graham, Janice (2010) Standardization and omics science : technical and social dimensions are inseparable and demand symmetrical study. OMICS: A Journal of Integrative Biology, 14(3), pp. 327-332.

[img] Accepted Version (PDF 175kB)
Administrators only | Request a copy from author

View at publisher


Standardization is critical to scientists and regulators to ensure the quality and interoperability of research processes, as well as the safety and efficacy of the attendant research products. This is perhaps most evident in the case of “omics science,” which is enabled by a host of diverse high-throughput technologies such as genomics, proteomics, and metabolomics. But standards are of interest to (and shaped by) others far beyond the immediate realm of individual scientists, laboratories, scientific consortia, or governments that develop, apply, and regulate them. Indeed, scientific standards have consequences for the social, ethical, and legal environment in which innovative technologies are regulated, and thereby command the attention of policy makers and citizens. This article argues that standardization of omics science is both technical and social. A critical synthesis of the social science literature indicates that: (1) standardization requires a degree of flexibility to be practical at the level of scientific practice in disparate sites; (2) the manner in which standards are created, and by whom, will impact their perceived legitimacy and therefore their potential to be used; and (3) the process of standardization itself is important to establishing the legitimacy of an area of scientific research.

Impact and interest:

11 citations in Scopus
Search Google Scholar™
4 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 34082
Item Type: Journal Article
Refereed: Yes
Keywords: Standardization, Omics
DOI: 10.1089/omi.2010.0022
ISSN: 1536-2310
Subjects: Australian and New Zealand Standard Research Classification > LAW AND LEGAL STUDIES (180000) > OTHER LAW AND LEGAL STUDIES (189900) > Law and Legal Studies not elsewhere classified (189999)
Divisions: Current > QUT Faculties and Divisions > Faculty of Law
Current > Research Centres > Australian Centre for Health Law Research
Current > Schools > School of Law
Copyright Owner: Mary Ann Liebert, Inc. publishers.
Deposited On: 12 Aug 2010 01:36
Last Modified: 17 Mar 2015 08:22

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page