QUT ePrints

Zinc supplementation at conventional doses does not improve the disturbance of taste perception in hemodialysis patients

Matson, Andrew, Wright, Mark, Oliver, Alister, Woodrow, Graham, King, Neil, Dye, Louise, Blundell, John, Brownjohn, Aleck, & Turney, John (2003) Zinc supplementation at conventional doses does not improve the disturbance of taste perception in hemodialysis patients. Journal of Renal Nutrition, 13(3), p. 224.

View at publisher

Abstract

Objective: To determine the effect of zinc supplementation on taste perception in a group of hemodialysis patients. Design and Setting: Double-blind randomized placebo-controlled study in a teaching hospital dialysis unit. Patients: Fifteen stable hemodialysis patients randomized to placebo (6 male, 2 female; median age, 67; range, 30 to 72 years) or treatment (5 male, 2 female; median age, 60; range, 31 to 76 years). Intervention: Treatment group received zinc sulfate 220 mg per day for 6 weeks, and the placebo group received an apparently identical dummy pill. Main Outcome Measures: Taste scores by visual analogue scales, normalized protein catabolic rate and plasma, whole blood and red cell zinc levels. Results: At baseline, sweet and salt tastes were identified correctly by both groups. Sour was often confused with salt. Sour solutions of different concentrations were not distinguishable. Taste scores were not different after 6 weeks for either group. There was no significant increment in zinc levels or normalized protein catabolic rate for either group. Conclusion: We found a disturbance of taste perception in hemodialysis patients, particularly for the sour modality, which was not corrected by this regimen of zinc supplementation. These results cast doubts on the conclusions of earlier studies that indicated an improvement in taste after zinc supplementation.

Impact and interest:

12 citations in Scopus
Search Google Scholar™
10 citations in Web of Science®

Citation countsare sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 34259
Item Type: Journal Article
DOI: 10.1016/S1051-2276(03)00072-4
ISSN: 10512276
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > HUMAN MOVEMENT AND SPORTS SCIENCE (110600)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Exercise & Nutrition Sciences
Deposited On: 27 Aug 2010 12:54
Last Modified: 29 Feb 2012 23:58

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page