Development of a multi-scale finite element model of the osteoporotic lumbar vertebral body for the investigation of apparent level vertebra mechanics and micro-level trabecular mechanics.
McDonald, Katrina A., Little, J. Paige, Pearcy, Mark J., & Adam, Clayton J. (2010) Development of a multi-scale finite element model of the osteoporotic lumbar vertebral body for the investigation of apparent level vertebra mechanics and micro-level trabecular mechanics. Medical Engineering & Physics, 32(6), pp. 653-661.
Osteoporotic spinal fractures are a major concern in ageing Western societies. This study develops a multi-scale finite element (FE) model of the osteoporotic lumbar vertebral body to study the mechanics of vertebral compression fracture at both the apparent (whole vertebral body) and micro-structural (internal trabecular bone core)levels. Model predictions were verified against experimental data, and found to provide a reasonably good representation of the mechanics of the osteoporotic vertebral body. This novel modelling methodology will allow detailed investigation of how trabecular bone loss in osteoporosis affects vertebral stiffness and strength in the lumbar spine.
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|Item Type:||Journal Article|
|Keywords:||Finite Element, vertebral mechanics, osteoporosis, trabecular mechanics, multi-scale model, vertebral compression fracture|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)|
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2010 IPEM Published by Elsevier Ltd.|
|Deposited On:||07 Sep 2010 01:29|
|Last Modified:||29 Feb 2012 14:16|
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